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Retatrutide 15 mg vial: water, concentration and units

A 15 mg Retatrutide vial with 2 mL of water is 7.5 mg/mL, so one unit on a U-100 syringe holds 75 mcg and 10 units hold 750 mcg.

Other water volumes and syringes are below. Unit conversion only.

Quick reference

Retatrutide 15 mg vial at common water volumes
Water addedConcentration1 unit (U-100)10 units
1 mL15 mg/mL150 mcg1.5 mg
2 mL7.5 mg/mL75 mcg750 mcg
3 mL5 mg/mL50 mcg500 mcg
mg
mL

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Concentration

7.5mg/mL

Enter an amount to see the syringe reading.

0102030405060708090100
U-100, 1 mL (100 units): empty. Enter values to see the reading.

What each reading holds

Units (U-100)mLHolds
100.1750 mcg
250.251.875 mg
500.53.75 mg
10017.5 mg
Work backwards: how much water?

Pick how many units you want your amount to read, and this gives the water volume that produces that concentration for Retatrutide.

units

Enter the vial amount and the amount to measure first.

Math only. Check every number against your vial label.

By [Author name]. Licensed pharmacist review: pending. Last updated .

The math for this vial

  1. Concentration: 15 mg ÷ 2 mL = 7.5 mg/mL (7,500 mcg/mL).
  2. Volume of one U-100 unit: 1 ÷ 100 = 0.01 mL.
  3. Mass in one unit: 7,500 mcg/mL × 0.01 mL = 75 mcg.
  4. The whole vial is 200 U-100 units of solution, more than one 1 mL syringe holds.

On a U-40 syringe each unit is 0.025 mL, so each unit holds 2.5 times as much: 187.5 mcg at 2 mL. See U-100 vs U-40 units.

Unit chart

What common U-100 readings hold from a 15 mg vial, by water volume.

UnitsmL1 mL water2 mL water3 mL water
10.01150 mcg75 mcg50 mcg
50.05750 mcg375 mcg250 mcg
100.11.5 mg750 mcg500 mcg
200.23 mg1.5 mg1 mg
250.253.75 mg1.875 mg1.25 mg
500.57.5 mg3.75 mg2.5 mg
100115 mg7.5 mg5 mg

About this vial size

15 mg is a mid-size Retatrutide vial. Across the water volumes above, one U-100 unit holds between 50 mcg (at 3 mL) and 150 mcg (at 1 mL). Compared with a 10 mg vial at the same water volume, it is 1.5 times as concentrated, so the same mass takes 0.67 times the units. A 20 mg vial at the same water volume is 1.33 times as concentrated as this one.

Vial sizes for retatrutide span a wide range, so the same volume of water gives very different concentrations. 2 mL in a 5 mg vial is 2.5 mg/mL; 2 mL in a 30 mg vial is 15 mg/mL, six times stronger. Re-check the vial size every time; it is the most common input mistake.

Storage and handling

  • No approved label exists for retatrutide, so there is no official storage or in-use stability data. Published stability data for reconstituted research material is also absent.
  • General lab practice for lyophilized peptides: store sealed vials cold and away from light; after reconstitution keep the vial refrigerated (2-8 °C), do not freeze it, and label it with the date and concentration.

Retatrutide is an investigational Eli Lilly drug in Phase 3 trials. It is not FDA-approved, cannot be legally compounded, and FDA has issued warning letters to online sellers of "research" retatrutide.

Retatrutide 15 mg vial questions

How much water goes in a 15 mg Retatrutide vial?

Any volume works; water only sets the concentration. 1 mL gives 15 mg/mL, 2 mL gives 7.5 mg/mL, 3 mL gives 5 mg/mL. Less water packs more mass into each syringe unit (harder to read precisely); more water spreads it out.

How many mcg are in one unit of a 15 mg vial?

On a U-100 syringe, one unit is 0.01 mL. With 1 mL of water, one unit holds 150 mcg; With 2 mL of water, one unit holds 75 mcg; With 3 mL of water, one unit holds 50 mcg.

How many units is 1 mg from a 15 mg vial?

At 1 mL of water, 1 mg is 6.7 units (0.067 mL). At 2 mL of water, 1 mg is 13.3 units (0.133 mL). At 3 mL of water, 1 mg is 20 units (0.2 mL). This is a unit conversion, not an amount to use.

Sources

  1. Eli Lilly: What to know about retatrutide
  2. Jastreboff AM et al. Triple-hormone-receptor agonist retatrutide for obesity: a phase 2 trial. N Engl J Med. 2023
  3. Rosenstock J et al. Retatrutide for people with type 2 diabetes: a phase 2 trial. Lancet. 2023
  4. Coskun T et al. LY3437943, a novel triple GIP, GLP-1 and glucagon receptor agonist. Cell Metab. 2022
  5. PubChem: Retatrutide
  6. FDA warning letter to Peptide Partners LLC, #735063 (2026-08-24)
  7. WADA Prohibited List